E-selectin is involved in mediating the adhesion of breast, colonic and renal carcinoma cells to the endothelium and inhibition reduces adherence 12, Breast cancer cell lines induce the expression of E-selectin on vascular endothelium .Cited by: Major adhesion molecules that are involved in lung cancer spread include E-cadherin, intercellular adhesion molecule (ICAM)-1, and E-selectin. E-cadherin is a prime adhesion molecule on epithelial cells mediating cell adhesion in homotypic fashion. 17 x 17 KemLer, ma-albany.info by:
Figure 1 E-selectin induces shear-resistant adhesion and transendothelial migration via interaction between E-selectin and CD (a) Effect of E-selectin on the shear-resistant adhesion of breast cancer cells to endothelial cells under physiological flow. A monolayer of Tet-on inducible E-selectin endothelial cells was grown on the chamber and incubated with doxycycline (1, ng/ml) for 5 ma-albany.info by: Jul 01, · Circulating intercellular adhesion molecule-1 (ICAM-1), E-selectin and vascular cell adhesion molecule-1 (VCAM-1) in human malignancies Skip to Cited by:
E-selectin is a receptor adhesion molecule which is implicated in colon and prostate cancer metastases. Breast cancer frequently spreads to bone where E-selectin is constitutively expressed. Moreover, E-selectin levels are increased in breast cancer patients with metastases. Hence we hypothesized that endothelial E-selectin and its ligands mediate breast cancer cell adhesion to . Oct 24, · Flow chamber adhesion and dynamic biochemical tissue analysis (DBTA) assays were used to evaluate whether Gal-1 modulates E-selectin adhesive interactions of breast cancer cells and tissues under dynamic flow conditions, while immunocytochemistry, immunohistochemistry, western blotting, and fluorescence anisotropy were used to study molecular interactions under static ma-albany.info by: 1.